Whakaahuatanga

Ko te konutai Sugammadex he hangahanga γ-cyclodextrin, ka mahi hei kaihoko whakahuri hou mo te poraka neuromuscular.

Ingoa Aano: sugammadex (soo GAM ma dex)
Ingoa Waitohu: Bridion

Ka whakatakahia e Sugammadex nga paanga o etahi rongoa ka tukuna i te wa o nga mahi pokanga hei whakangawari i o uaua.

Ka whakamahia te Sugammadex i te mutunga o te pokanga, hei awhina i te whakaora i nga mahi uaua kua aukatia i te wa e pokanga ana e etahi atu rongoa.

Ka taea ano te whakamahi a Sugammadex mo nga kaupapa kaore i te raarangi i tenei aratohu rongoa.

Ka whakamahia hei huri i nga paanga o etahi raau taero.

I roto i te Vivo

Ko te werohanga o te sugammadex karekau he paanga nui ki te pehanga toto me te reiti ngakau.I muri i te werohanga o te horopeta nui o te rocuronium, ko te 90% te whakaora o te tereina-o-wha owehenga e 28 min (SD 7 min) i muri i te saline, 26 min (SD 9.5 min) i muri i te 1 mg / kg sugammadex, me te 8 min (SD 3.6 min) i muri i te 2.5 mg / kg sugammadex [1].Ko te Sugammadex he tere me te tino hurihanga o te paraka neuromuscular na te rocuronium.Ko te wa whakaora ki te whakangungu i te wha tauwehenga=0.9 i muri i te whakaora ohorere he 14.4 min (SD=3.4 min; n=14).Ka tino whakahekehia tenei ki te 3.7 min (SD = 3.3 min; n = 4) me te sugammadex 0.5 mg / kg me te 1.9 min (SD = 1.0 min; n = 4) me te sugammadex 1.0 mg / kg [2].Ko te haurua-ora o te sugammadex i roto i te makimaki Rhesus he 30 (SEM=4.9) min[3].

Rokiroki

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