Relugolix 737789-87-6

Whakaahuatanga Poto:

Ingoa API Tohutohu Whakatakotoranga US DMF EU DMF CEP
Ribociclib CAS: 737789-87-6 Atineoplastic Roto-whare      


Taipitopito Hua

Tohu Hua

WHAKAMAHI HUA

Ka whakamahia a Relugolix ki te rongoa i te mate pukupuku prostate i roto i nga tane.
Ingoa Waitohu: Orgovyx
Karaehe Ta'auau: Atineoplastic - LHRH (GnRH) Antagonist Pituitary Suppressants
Wātea: E hiahiatia ana te whakahaunga
Haputanga: Me toro atu ki to taakuta.Ka kino pea tenei rongoa ki te tamaiti kare i whanau.
Whakahau: Me korero ki te taote i mua i te whakamahi

Ko te Relugolix he homoni tuku gonadotropin-kore-peptide (GnRH, luteinizing hormone-releasing hormone (LHRH)) antagonist, me te mahi antineoplastic pea.Ka herea e Relugolix te whakataetae me te aukati i te kaiwhakawhiwhi GnRH i roto i te repe pituitary o mua, e aukati ana i te herenga o te GnRH ki te kaiawhina GnRH me te aukati i te hunanga me te tuku o te taiaki luteinizing (LH) me te homoni whakaihiihi follicle (FSH).I roto i nga tane, ko te aukati o te hunanga LH ka aukati i te tukunga o te testosterone mai i nga pūtau Leydig i roto i nga whakamatautau.I te mea e hiahiatia ana te testosterone kia mau tonu te tipu o te prostate, ko te whakaheke i nga taumata testosterone ka aukati i te tipu o te mate pukupuku prostate e whakawhirinaki ana ki te homoni.

Ko te Relugolix he homone tuku gonadotropin-releasing hormone (GnRH) antagonist i whakamahia i roto i te maimoatanga o te maha o nga tikanga urupare-hormone.I whakaaetia tuatahi i Japan i te tau 2019, i raro i te ingoa tohu Relumina, mo te maimoatanga tohu o te fibroids uterine, me te mea tata nei na te United States 'FDA i 2020, i raro i te ingoa waitohu Orgovyx, mo te maimoatanga o te mate pukupuku prostate matatau.Kua akohia ano a Relugolix mo te maimoatanga tohu o te endometriosis.Ko Relugolix te tuatahi (a i tenei wa anake) ka tukuna-waha-waha te GnRH antagonist i whakaaetia mo te maimoatanga o te mate pukupuku prostate - he rite nga rongoa penei i te [degarelix] e hiahia ana ki te whakahaere i raro i te kiri - na reira ka whakarato i tetahi waahanga rongoa iti ake te taumaha mo nga turoro e hiahia ana kia toro atu ki te whare haumanu. mo te whakahaere a nga tohunga hauora.I tua atu i te ngawari o te whakamahi, i whakaatuhia he pai ake te relugolix i roto i te paheketanga o nga taumata testosterone ina whakaritea ki te [leuprolide], tetahi atu rongoa whakaheke androgen e whakamahia ana mo te maimoatanga o te mate pukupuku prostate.

Ko Relugolix he Gonadotropin Releasing Hormone Receptor Antagonist.Ko te tikanga o te mahi o te relugolix ko te Gonadotropin Releasing Hormone Receptor Antagonist, me te Cytochrome P450 3A Inducer, me te Cytochrome P450 2B6 Inducer, me te Breast Cancer Resistance Protein Inhibitor, me te P-Glycoprotein Inhibitor.Ko te awe o te relugolix na te whakahekenga o te hunanga o te GnRH.

Hanganga matū

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Tiwhikete

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

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